Super Eagles goalkeeper Maduka Okoye will not be available for the crucial World Cup game between his side and Blackstars on Friday.
We understand Maduka Okoye tested positive for Covid-19 and would not be available for the first leg.
The Sparta Rotterdam was unable to board the flight from Netherlands to Abuja.
John Noble who plays for Enyimba FC has been called in to replace Maduka Okoye.
This is a huge blow to Nigeria as three keys players have been ruled out of the first leg due to injury or ailment.
Ndidi, Kenneth Omerou and Okoye are all out for the first leg in Ghana.
These three players were an integral part of the Nigeria squad that played in just ended AFCON in Cameroon.
In a related development, Ghana have been sweating over the fitness of Jordan Ayew due to Covid but he has recovered to be part of the squad,.
Ghana will host Nigeria in the first leg of the 2022 World Cup qualifiers game on Friday, March 25, and the second leg in Abuja on March 29.